ID2 Protein
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ID2 Protein Definition
A member of the "ID" subfamily, ID2 promotes cell cycle progression by inhibiting RB, p107, and p130. By increasing ID2 expression, MYC overrides RB suppression of ID2 action. Since ID2 lacks a DNA-binding domain it must work through dimerization with other HLH transcription factors. (from SWISS-PROT Q02363, OMIM 600386, and NCI)
ID2 Protein Synonyms
ID2 Protein, DNA-Binding Protein Inhibitor ID-2, ID2, Inhibitor of DNA Binding 2, Inhibitor of DNA Binding 2, Dominant Negative Helix-Loop-Helix Protein, Inhibitor of Differentiation 2
Terms in ID2 Protein category
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