IGF-1R Inhibitor OSI-906
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IGF-1R Inhibitor OSI-906 Definition
An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGFR-1 stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis.
IGF-1R Inhibitor OSI-906 Synonyms
IGF-1R Inhibitor OSI-906, OSI-906
Terms in IGF-1R Inhibitor OSI-906 category
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