IKZF1 wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> IKZF1 Gene -> IKZF1 wt Allele

IKZF1 wt Allele Definition

Human IKZF1 wild-type allele is located within 7p13-p11.1 and is approximately 123 kb in length. This allele, which encodes DNA-binding protein Ikaros, plays a role in transcriptional enhancement. Truncated and mutated forms of the gene can be a factor in acute lymphoblastic leukemia. A translocation t(3;7)(q27;p12) that fuses the gene to the BCL6 gene is implicated in diffuse large B-cell lymphomas.

IKZF1 wt Allele Synonyms

IKZF1 wt Allele, Hs.54452, IK1, IKAROS, IKAROS Family Zinc Finger 1 (Ikaros) wt Allele, IKZF1, LYF1, PRO0758, ZNFN1A1, hIk-1

Terms in IKZF1 wt Allele category

---

Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.