IL-2 Recombinant Fusion Protein ALT-801
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IL-2 Recombinant Fusion Protein ALT-801 Definition
A recombinant protein consisting of the cytokine interleukin-2 (IL-2) fused to a humanized soluble T-cell receptor (TCR) directed against a tumor suppressor p53-derived antigen with potential immunopotentiating and antineoplastic activities. The TCR moiety of IL-2 recombinant fusion protein ALT-801 binds to tumor cells displaying p53 epitope/MHC complexes; subsequently, the tumor cell-localized IL-2 moiety may stimulate natural killer (NK) cell and T cell cytotoxic immune responses against p53-expressing tumor cells.
IL-2 Recombinant Fusion Protein ALT-801 Synonyms
IL-2 Recombinant Fusion Protein ALT-801, ALT-801
Terms in IL-2 Recombinant Fusion Protein ALT-801 category
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