IMP-Dehydrogenase-2
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IMP-Dehydrogenase-2 Definition
Encoded by 14-exon 6-kb human IMPDH2 Gene (IMPDH/GMPR Family), homotetrameric 514-aa 56-kDa IMP Dehydrogenase 2 is the rate-limiting enzyme in de novo guanine nucleotide synthesis, contains 2 CBS domains, and contains a blocked N-terminus. Involved in regulation of cell proliferation, IMPDH2 catalyzes the first step in GMP biosynthesis from IMP. (NCI)
IMP-Dehydrogenase-2 Synonyms
IMP Dehydrogenase 2
Terms in IMP-Dehydrogenase-2 category
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