Cancer Terms

Ifosfamide

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Mustard Agent -> Nitrogen Mustard Compound -> Ifosfamide

Ifosfamide Definition

A synthetic analogue of the nitrogen mustard cyclophosphamide with antineoplastic activity. Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes. (NCI04)

Ifosfamide Synonyms

Ifosfamide, 2-oxo-N,3-bis-(2-chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin- 2-amine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, IFO, IFO-Cell, IFOSFAMIDE, IFX, Ifex, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, MJF 9325, MJF-9325, Mitoxana, N,3-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, ifosfamide

Terms in Ifosfamide category



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