IgG-Fc-Receptor-IIIA
Cancer Terms ->
Gene Product ->
Protein ->
Protein Organized by Function ->
Ligand Binding Protein ->
Receptor ->
Cell Surface Receptor ->
Fc Receptor ->
Fc-Gamma Receptor-III -> IgG-Fc-Receptor-IIIA
IgG-Fc-Receptor-IIIA Definition
Expressed on natural killer cells, macrophages, T cells, immature thymocytes, and trophoblasts by human FCGR3A Gene, 254-aa 29-kDa (precursor) glycosylated IgG Fc Receptor IIIA is a putative type I membrane protein containing 2 IgC2 domains and a receptor for the Fc region of monomeric or aggregated IgG that mediates antibody-dependent responses, such as phagocytosis and antibody-dependent cellular cytotoxicity. FCGR3B exists in a hetero-oligomeric complex with the Fc epsilon receptor I gamma subunit and/or the CD3 zeta subunit, as a soluble receptor produced by proteolytic cleavage. Amino acid conservation between CD16, other Fc receptors, and related Ig suggest similar structures and modes of association. (NCI)
IgG-Fc-Receptor-IIIA Synonyms
IgG Fc Receptor IIIA, CD16, CD16A, FCG3, FCGR3, FCGR3A, Fc-Gamma RIII, Fc-Gamma RIII-Alpha, Fc-Gamma RIIIA, FcR-10, FcRIII, FcRIIIA, IGFR3, IgG Fc Receptor III-2, Low Affinity IgG Fc Receptor IIIA, Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A
Terms in IgG-Fc-Receptor-IIIA category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.