Imidazole Mustard
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Imidazole Mustard Definition
A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis. (NCI04)
Imidazole Mustard Synonyms
Imidazole Mustard, 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]-imidazole-4-carboxamide, 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide, 5-[3,3-Bis(2-Chloroethyl)-1-Triazeno]Imidazole-4-Carboxamide, BIC, Imidazole mustard, TIC Mustard, TIC mustard
Terms in Imidazole Mustard category
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