Cancer Terms

Insulin Receptor Substrate-2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> Adaptor Signaling Protein -> Insulin Receptor Substrate-2

Insulin Receptor Substrate-2 Definition

Similar in function to IRS1; insulin receptor substrate 2 is a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS2 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS2 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin-4 receptor (IL4R) -associated kinase in response to IL4 treatment. (LocusLink)

Insulin Receptor Substrate-2 Synonyms

Insulin Receptor Substrate 2, IRS2

Terms in Insulin Receptor Substrate-2 category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.