Insulin-Like Growth Factor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Growth Factor -> Insulin-Like Growth Factor

Insulin-Like Growth Factor Definition

Bound to IGFBPs in the circulation, Insulin-Like Growth Factors (IGFs, Somatomedins) are a family of extracellular signaling peptides (potential autocrine ligands) involved in mediation of growth hormone action, stimulation of insulin action, and growth and development. The three main somatomedins are Somatomedin C (IGF1), Somatomedin A (IGF2), and Somatomedin B. Single chain IGFs I and II share about 47% amino acid homology with insulin (INS) and 31% with relaxin.

Insulin-Like Growth Factor Synonyms

Insulin-Like Growth Factor, IGF, Somatomedin

Terms in Insulin-Like Growth Factor category

Insulin-Like Growth Factor-1
Insulin-Like Growth Factor-2