Insulin-Like Growth Factor-Binding Protein-2

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Insulin-Like Growth Factor-Binding Protein -> Insulin-Like Growth Factor-Binding Protein-2

Insulin-Like Growth Factor-Binding Protein-2 Definition

Encoded by human IGFBP2 Gene, cysteine-rich high molecular weight secreted 328-aa 35-kD Insulin-Like Growth Factor-Binding Protein 2 precursor contains an IGFBP domain and a thyroglobulin type-I domain. IGF-binding proteins prolong plasma IGF half-life and alter IGF interaction with cell surface receptors. The predominant form in plasma (150-kD) contains IGF-BP53 with apparent molecular mass of 53-kD. IGFBP2 binds IGF-II with high affinity more than IGF-I. (from LocusLink, Swiss-Prot, OMIM, and NCI)

Insulin-Like Growth Factor-Binding Protein-2 Synonyms

Insulin-Like Growth Factor-Binding Protein 2, IBP-2, IBP2, IGF Binding Protein 2, IGF-BP53, IGFBP-2, IGFBP2, Insulin-Like Growth Factor Binding Protein 2, Insulin-Like Growth Factor Binding Protein 2 (36kD), Insulin-Like Growth Factor Binding Protein 2, 36kDa

Terms in Insulin-Like Growth Factor-Binding Protein-2 category

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