Cancer Terms

Integrin Alpha-X

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Cell Adhesion Molecule -> Integrin Alpha-X

Integrin Alpha-X Definition

Leukocyte Surface Antigen p150,95 has a unique alpha chain (CD11c) and shares a beta subunit (CD18) with two other members of the leukocyte adhesion molecule family. The alpha subunit has an extracellular domain containing ten potential glycosylation sites, a transmembrane domain, and a short cytoplasmic tail. It shows homology to alpha subunits of Platelet Glycoprotein IIb/IIIa, Vitronectin Receptor, and Fibronectin Receptor. Receptors involved in cell-cell and cell-matrix interactions belong to a superfamily of integrin genes. (from OMIM 151510 and NCI)

Integrin Alpha-X Synonyms

Integrin Alpha X, Alphax Integrin Chain, Antigen Cd11c (P150), Alpha Polypeptide, Axb2, CD11c, Cr4, ITGAX, Leukocyte Surface Antigen P150, 95, Myeloid Membrane Antigen, Alpha Subunit

Terms in Integrin Alpha-X category



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