Interferon Regulatory Factor-3
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Interferon Regulatory Factor-3 Definition
IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. (from LocusLink)
Interferon Regulatory Factor-3 Synonyms
Interferon Regulatory Factor 3, IRF3
Terms in Interferon Regulatory Factor-3 category
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