Cancer Terms

Interferon Regulatory Factor-3

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Interferon Regulatory Factor-3

Interferon Regulatory Factor-3 Definition

IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. (from LocusLink)

Interferon Regulatory Factor-3 Synonyms

Interferon Regulatory Factor 3, IRF3

Terms in Interferon Regulatory Factor-3 category



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