Cancer Terms

Interferon Regulatory Factor-4

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Transcription Regulatory Protein -> Transcription Factor -> Interferon Regulatory Factor-4

Interferon Regulatory Factor-4 Definition

Interferon regulatory factor 4 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter and to the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in the ISRE-targeted signal transduction mechanisms of lymphoid cells. Two isoforms are produced by alternative splicing. (from OMIM 601900 and NCI)

Interferon Regulatory Factor-4 Synonyms

Interferon Regulatory Factor 4, IRF4, IRF4 Protein, ISRE DNA Binding Protein, Interferon Stimulated Response Element DNA Binding Protein, LSIRF Protein, Lymphocyte-Specific IRF

Terms in Interferon Regulatory Factor-4 category



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