Cancer Terms

Interleukin-17

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Cytokine -> Interleukin -> Interleukin-17

Interleukin-17 Definition

Interleukin 17 is a homodimer expressed in stimulated, but not resting, cytotoxic T-cells that induces stromal cells to produce pro-inflammatory and hematopoietic cytokines. IL17 enhances expression of IL6, IL8, and ICAM-1 in fibroblasts and appears to induce osteoclastogenesis and ODF, a membrane-associated protein essential to osteoclast differentiation. IL17 has sequence similarity to the herpesvirus saimiri immediate early gene 13 protein. (from OMIM 603149 and NCI)

Interleukin-17 Synonyms

Interleukin-17, CTLA-8, CTLA8, Cytotoxic T-Lymphocyte-Associated Antigen 8, Cytotoxic T-Lymphocyte-Associated Serine Esterase 8, IL-17, IL-17A, IL17, IL17 Protein, IL17A, Interleukin 17, Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8), Interleukin 17 Precursor

Terms in Interleukin-17 category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.