Interleukin-17
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Interleukin-17 Definition
Interleukin 17 is a homodimer expressed in stimulated, but not resting, cytotoxic T-cells that induces stromal cells to produce pro-inflammatory and hematopoietic cytokines. IL17 enhances expression of IL6, IL8, and ICAM-1 in fibroblasts and appears to induce osteoclastogenesis and ODF, a membrane-associated protein essential to osteoclast differentiation. IL17 has sequence similarity to the herpesvirus saimiri immediate early gene 13 protein. (from OMIM 603149 and NCI)
Interleukin-17 Synonyms
Interleukin-17, CTLA-8, CTLA8, Cytotoxic T-Lymphocyte-Associated Antigen 8, Cytotoxic T-Lymphocyte-Associated Serine Esterase 8, IL-17, IL-17A, IL17, IL17 Protein, IL17A, Interleukin 17, Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8), Interleukin 17 Precursor
Terms in Interleukin-17 category
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