Cancer Terms

Interleukin-2 Receptor Gamma

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Receptor -> Cell Surface Receptor -> Cytokine Receptor -> Interleukin-2 Receptor Gamma

Interleukin-2 Receptor Gamma Definition

The interleukin 2 (IL2) receptor gamma chain (IL2RG) is an important signalling component of many interleukin receptors (e.g., IL2,IL4,IL7,IL9, and IL15) and is thus referred to as the common gamma chain. It is necessary for normal growth and differentiation of T cells, B cells, natural killer cells, glioma cells, and cells of the monocyte lineage. Mutations in this X-chromosome-linked gene cause X-linked severe combined immunodeficiency (XSCID). (from LocusLink and OMIM)

Interleukin-2 Receptor Gamma Synonyms

Interleukin 2 Receptor Gamma, CD132, Common Cytokine Receptor Gamma Chain, Common Gamma Chain, IL2RG, Interleukin 2 Receptor, Gamma, Interleukin 2 Receptor, Gamma Chain

Terms in Interleukin-2 Receptor Gamma category



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