Interleukin-4
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Interleukin-4 Definition
Human interleukin-4 protein (153 aa, 17.5 kDa precursor) is encoded by the human interleukin-4 (IL4) gene. Two isoforms of this protein are expressed by activated T cells. This protein is a pleiotropic soluble cytokine that is a ligand for the interleukin 4 receptor. This receptor-ligand interaction induces expression of MHC II and Fc receptors on B-cells, causing proliferation and differentiation of these cells.
Interleukin-4 Synonyms
Interleukin-4, B Cell Proliferating Factor, B-Cell Differentiation Factor-1, B-Cell Growth Factor, B-Cell Growth Factor-1, B-Cell Stimulating Factor, B-Cell Stimulation Factor-1, B-Cell Stimulatory Factor 1, BCDF-1, BCGF, BCGF-1, BCSF 1, BSF-1, BSF1, IL-4, IL4, IL4 Protein, Interleukin 4, Interleukin-4 Precursor, Lymphocyte Stimulatory Factor 1, MCGF 2, Mast Cell Growth Factor-2, T-Cell Growth Factor 2, interleukin-4
Terms in Interleukin-4 category
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