Interleukin-7
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Interleukin-7 Definition
Encoded by human IL7 Gene, Interleukin-7 is an important cytokine for B and T cell development. This cytokine and HGF form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 is a cofactor for V(D)J rearrangement of T cell receptor beta (TCRB) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may be a regulatory factor for intestinal mucosal lymphocytes. Studies in mice suggest that IL7 plays an essential role in lymphoid cell survival. (From LocusLink)
Interleukin-7 Synonyms
Interleukin-7, IL-7, IL7, IL7 Protein, Interleukin 7 Precursor, Lymphopoietin-1
Terms in Interleukin-7 category
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