Iodine I 124-Iodo-Azomycin Galactopyranoside
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Radioconjugate -> Iodine I 124-Iodo-Azomycin Galactopyranoside
Iodine I 124-Iodo-Azomycin Galactopyranoside Definition
A diagnostic radiopharmaceutical comprised of iodo-azomycin galactopyranoside (IAZGP) labeled with the positron-emitting radioisotope iodine I 124 and used as an imaging agent. Iodine I 124 iodo-azomycin galactopyranoside (I-124 IAZGP) is reduced under hypoxic conditions, covalently binding to macromolecules in hypoxic cells. After incorporation into hypoxic tumor cell DNA, I-124 IAZGP can be localized and quantified using positron emission tomography (PET), allowing a quantitative assessment of hypoxic tumor burden. IAZGP appears to have a higher water solubility and faster clearance from normal tissue than traditional imidazole tracers.
Iodine I 124-Iodo-Azomycin Galactopyranoside Synonyms
Iodine I 124-Iodo-Azomycin Galactopyranoside, I-124 IAZGP
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