Iodine I 131 MIP-1145
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Iodine I 131 MIP-1145 Definition
An iodine 131-radiolabeled small-molecule benzamide compound with potential antineoplastic activity. The benzamide moiety of 131-I-MIP-1145 binds to melanin, selectively delivering a cyotoxic dose of gamma and beta radiation to melanin-expressing tumor cells. Melanin pigments, polymer derivatives of the amino acid tyrosine, are over-expressed in approximately 40% of melanomas.
Iodine I 131 MIP-1145 Synonyms
Iodine I 131 MIP-1145, 131-I-MIP-1145, N-(2-diethylamino-ethyl)-4-(4-F-benzamido)-5-iodo-2-methoxy-benzamide
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