Irbesartan
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Angiotensin II Receptor Antagonist -> Irbesartan
Irbesartan Definition
A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. (NCI05)
Irbesartan Synonyms
Irbesartan, Avapro, IRBESARTAN
Terms in Irbesartan category
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