Cancer Terms

Isotretinoin

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Retinoic Acid Agent -> Isotretinoin

Isotretinoin Definition

A naturally-occurring retinoic acid with potential antineoplastic activity. Isotretinoin binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.

Isotretinoin Synonyms

Isotretinoin, 13-cRA, 13-cis retinoic acid, 13-cis-Retinoate, 13-cis-Retinoic Acid, 13-cis-Vitamin A Acid, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-trans-6-trans-8-trans-nonatetraenoic Acid, Accure, Accutane, Amnesteem, Cistane, Claravis, ISOTRETINOIN, Isotretinoinum, Isotrex, Isotrexin, Neovitamin A, Neovitamin A Acid, Oratane, Retinoicacid-13-cis, Ro 4-3780, Ro-4-3780, Roaccutan, Roaccutane, Roacutan, Sotret, cis-Retinoic Acid, isotretinoin

Terms in Isotretinoin category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.