Cancer Terms

KRAS2 wt Allele

Cancer Terms -> Gene -> Signaling Pathway Gene -> G Protein Gene -> RAS Family Gene -> KRAS2 Gene -> KRAS2 wt Allele

KRAS2 wt Allele Definition

Human KRAS wild-type allele is located in the vicinity of 12p12.1 and is approximately 45 kb in length. This allele, which encodes GTPase KRas protein, plays a role in the modulation of both cellular proliferation and differentiation. Mutations in the gene are associated with juvenile myelomonocytic leukemia, Noonan syndrome 3 and cardiofaciocutaneous syndrome.

KRAS2 wt Allele Synonyms

KRAS wt Allele, C-K-RAS, K-RAS2A, K-RAS2B, K-Ras 2A, KI-RAS, KRAS2, RASK2, v-Ki-RAS2 Kirsten Rat Sarcoma 2 Viral Oncogene Homolog wt Allele

Terms in KRAS2 wt Allele category



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