KSA-Interleukin-2 Fusion Protein
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KSA-Interleukin-2 Fusion Protein Definition
A recombinant fusion protein comprised of a human monoclonal antibody directed against the epithelial cell adhesion molecule (EpCAM or KS) linked to an active interleukin-2 (IL2) molecule with potential antineoplastic activity. The humanized monoclonal antibody moiety of huKS-IL2 fusion protein recognizes and binds to EpCAM, a cell surface epithelial protein that is expressed on a wide variety of cancer cells, thereby concentrating IL2 in EpCAM-expressing tumor tissue. Subsequently, the localized IL2 moiety of the fusion protein may stimulate a cytotoxic T-cell antitumor immune response.
KSA-Interleukin-2 Fusion Protein Synonyms
Tucotuzumab Celmoleukin, EMD 273066, KSA-IL-2, KSA-Interleukin-2 Fusion Protein, KSA-interleukin-2, huKS-IL2 Fusion Protein
Terms in KSA-Interleukin-2 Fusion Protein category
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