Cancer Terms

Kit Ligand

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Cytokine -> Hematopoietic Growth Factor -> Kit Ligand

Kit Ligand Definition

Stem Cell Factor is a hematopoietic growth factor, a key signal in mast cell differentiation and function, and a ligand for the KIT tyrosine kinase receptor CD117. In the mouse, this growth factor is encoded by Sl ('steel'), a gene critical to the development of several cell lineages as well as to hematopoiesis in the adult. SCF augments proliferation of myeloid and lymphoid progenitors. (from OMIM 184745 and NCI)

Kit Ligand Synonyms

Kit Ligand, C-Kit Ligand, KITLG, MGF, MGF Stem Cell Factor, Mast Cell Growth Factor, SCF, Steel Factor, Stem Cell Factor

Terms in Kit Ligand category



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