Cancer Terms

Ku70 Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Hydrolase -> Helicase -> Ku Protein -> Ku70 Protein

Ku70 Protein Definition

KU70 protein is the 70 kD subunit of the KU autoantigen, a heterodimeric DNA repair complex that binds DNA double-strand breaks, is the DNA-binding component of the DNA-dependent protein kinase, and facilitates repair by nonhomologous end-joining. KU70 and KU80 form a dyad-symmetrical molecule with a preformed ring that encircles duplex DNA. KU protein is also involved in V(D)J recombination. KU is identical to DNA helicase II, an ATP-dependent DNA unwinding enzyme. (from OMIM 152690 and NCI)

Ku70 Protein Synonyms

Ku70 Protein, ATP-Dependent DNA Helicase II, 70 kD Subunit, G22P1, La Protein, Lupus Autoantigen, Lupus Ku Autoantigen, Thyroid Autoantigen 70kD

Terms in Ku70 Protein category



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