LIM Homeobox Protein-1
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LIM Homeobox Protein-1 Definition
Encoded by conserved human LHX1 Gene (LIM/Homeobox Family) and expressed in brain, thymus, and tonsil, 384-404-amino acid 44.5-kD nuclear LIM Homeobox Protein 1 is a putative transcriptional regulatory protein containing two CYS-rich zinc ion-binding LIM domains and a DNA-binding homeobox domain. LIM1 may regulate the head organizer and control differentiation and development of neural and lymphoid cells. LIM1 and LMX1B appear to control lateral column motor axon dorsal/ventral trajectory in the developing limb. (from LocusLink, Swiss-Prot, OMIM, and NCI)
LIM Homeobox Protein-1 Synonyms
LIM/Homeobox Protein LHX1, Homeobox Protein LIM-1, LHX1, LHX1 Protein, LIM Homeobox Protein 1, LIM/Homeodomain Transcription Factor 1
Terms in LIM Homeobox Protein-1 category
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