LIM Homeobox Protein-2
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LIM Homeobox Protein-2 Definition
Related to 'apterous' (Drosophila) and encoded by human LHX2 Gene (LIM/Homeobox Family), 406-amino acid 44-kD nuclear LIM Homeobox Protein 2 is a putative transcription factor containing two CYS-rich zinc ion-binding LIM domains and a DNA-binding homeobox domain. LIM2 may control differentiation and development of neural and lymphoid cells. Rodent LH2 is expressed in the central nervous system and in immature B- and T-cells. In the pituitary, mouse Lh2 regulates expression of the pituitary glycoprotein hormone alpha subunit. High expression is observed in chronic myelogenous leukemia (CML). (from LocusLink, Swiss-Prot, OMIM, and NCI)
LIM Homeobox Protein-2 Synonyms
LIM/Homeobox Protein LHX2, Homeobox Protein LH-2, LHX2, LHX2 Protein, LIM Homeobox Protein 2, LIM/Homeodomain Transcription Factor 2
Terms in LIM Homeobox Protein-2 category
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