Cancer Terms

Large Tumor Suppressor Homolog-2 Protein

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Large Tumor Suppressor Homolog-2 Protein Definition

Expressed in many tissues (highest in heart and skeletal muscle) and encoded by human LATS2 Gene (SER/THR PK Family), the 125-kD nuclear Ser/Thr protein kinase Large Tumor Suppressor Homolog 2 contains seven PAPA repeats (dipeptide proline-alanines likely involved in protein-protein interactions) and a C-terminal kinase domain. Human and mouse proteins are most closely related to LATS1 proteins, followed by Drosophila Lats. (from LocusLink, Swiss-Prot, OMIM, and NCI)

Large Tumor Suppressor Homolog-2 Protein Synonyms

Large Tumor Suppressor Homolog 2, LATS (Large Tumor Suppressor) Homolog 2, LATS2, LATS2 Protein, Large Tumor Suppressor 2, Tumor Suppressor LATS/WARTS Homolog 2

Terms in Large Tumor Suppressor Homolog-2 Protein category



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