Cancer Terms

Left-Right Determination Factor-B

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Growth Factor -> Transforming Growth Factor -> Transforming Growth Factor-Beta -> Left-Right Determination Factor-B

Left-Right Determination Factor-B Definition

Containing a TGF-beta family domain, similar to LEFTYA, and encoded by human LEFTB Gene (TGF-Beta Family), secreted 366-amino acid 41-kD Left-Right Determination Factor B (preproprotein) undergoes cell-specific alternative processing into three different products. Processing may occur at R-X-X-R sites. LEFTB appears required for left-right determination during early presomite development in mammals. It may serve as a feedback inhibitor to restrict the range of nodal signaling during establishment of the axis. (from LocusLink, Swiss-Prot, OMIM, and NCI)

Left-Right Determination Factor-B Synonyms

Left-Right Determination Factor B, LEFTB, Left-Right Determination Factor B Preproprotein, Lefty 2 Homolog, Lefty-B Protein

Terms in Left-Right Determination Factor-B category



Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods

No reproduction or republication permitted.