Licensing Factor

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Licensing Factor

Licensing Factor Definition

S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G(1), and passage through S-phase removes the license to replicate. Licensing factors are required for licensing and central to ensuring that replication occurs once per cell cycle. (from J Biol Chem 2001 Nov 30;276(48):44905-11)

Licensing Factor Synonyms

Licensing Factor

Terms in Licensing Factor category

CDC6 Cell Division Cycle-6 Homolog Protein
DNA Replication Factor
MCM Protein