Cancer Terms

Lomefloxacin Hydrochloride

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Antibiotic -> Quinolone Antibiotic -> Lomefloxacin Hydrochloride

Lomefloxacin Hydrochloride Definition

The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis.

Lomefloxacin Hydrochloride Synonyms

Lomefloxacin Hydrochloride, (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride, LOMEFLOXACIN HYDROCHLORIDE, Maxaquin, Mazaquin, NY 198

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