Cancer Terms

Loracarbef

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Anti-Infective Agent -> Antibiotic -> Cephalosporin Antibiotic -> Loracarbef

Loracarbef Definition

A semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic derived from cephasporium. The bactericidal activity of loracarbef results from the inhibition of bacterial cell wall synthesis through interference with the cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and causes cell lysis. Loracarbef is more active against a variety of gram-negative organisms but less active against gram-positive pathogens compared to first-generation agents.

Loracarbef Synonyms

Loracarbef, (6R, 7S)-7-[(R)-2-Amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, Monohydrate, LORACARBEF, Lorabid

Terms in Loracarbef category



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