MAP-Kinase-11
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Mitogen-Activated Protein Kinase -> MAP-Kinase-11
MAP-Kinase-11 Definition
Encoded by MAPK11 Gene, MAP Kinase 11 is a member of the MAP kinase family, integration points for multiple biochemical signals and involved in a variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MAPK11 is most closely related to p38 MAP kinase; both can be activated by proinflammatory cytokines and environment stress. MAPK11 is activated through phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of MAPK11. (NCI)
MAP-Kinase-11 Synonyms
MAP Kinase 11, MAPK11, Mitogen-Activated Protein Kinase P38-2, Stress-Activated Protein Kinase-2
Terms in MAP-Kinase-11 category
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