Cancer Terms

MAP-Kinase-4

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Enzyme -> Transferase -> Phosphotransferase -> Kinase -> Protein Kinase -> Serine-Threonine Protein Kinase -> Mitogen-Activated Protein Kinase -> MAP-Kinase-4

MAP-Kinase-4 Definition

Highly expressed in heart and brain by human MAPK4 Gene (MAPK Family), 557-aa 63-kDa MAP Kinase 4 is a Ser/Thr protein kinase activated by tyrosine kinase growth factor receptors that translocates to the nucleus to phosphorylate nuclear targets and likely promote entry in the cell cycle. MAPK4 also phosphorylates MAP2. (NCI)

MAP-Kinase-4 Synonyms

MAP Kinase 4, Extracellular Signal-Regulated Kinase 4, MAP Kinase Isoform P63, MAPK4

Terms in MAP-Kinase-4 category



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