MEK Inhibitor AZD8330
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MEK Inhibitor AZD8330 Definition
An orally active, selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor AZD8330 specifically inhibits mitogen-activated protein kinase kinase 1 (MAP2K1 or MAPK/ERK kinase 1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers.
MEK Inhibitor AZD8330 Synonyms
MEK Inhibitor AZD8330, ARRY-424704, ARRY-704, AZD8330
Terms in MEK Inhibitor AZD8330 category
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