Cancer Terms

MLH1 Protein

Cancer Terms -> Retired Concepts -> Retired Concept 2003 -> MLH1 Protein

MLH1 Protein Definition

MLH1 protein is a DNA-binding, DNA-mismatch repair protein, of the MutL/HexB family, that dimerizes with PMS2 or MLH3. MLH1 is part of the multi-subunit BASC repair complex containing ATM, BLM, MSH2, MSH6, BRCA1, the RAD50/MRE11/NBS1 complex, and the RFC1/RFC2/RFC4 complex. MLH1 is homologous to MutL, which hydrolyzes ATP. (from OMIM 120436 and NCI)

MLH1 Protein Synonyms

MLH1 Protein, MLH1 Gene Product, MUTL Protein Homolog 1, Mismatch DNA Repair Protein MLH1, hMLH1 Protein

Terms in MLH1 Protein category



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