MLH1 wt Allele

Cancer Terms -> Gene -> DNA Repair Gene -> MLH1 Gene -> MLH1 wt Allele

MLH1 wt Allele Definition

Human MLH1 wild-type allele is located in the vicinity of 3p21.3 and is approximately 57 kb in length. This allele, which encodes DNA mismatch repair protein Mlh1, plays a role in DNA mismatch repair. Aberrant alleles are associated with colon, endometrial and stomach cancers. Further, the defects in MLH1 are a cause of hereditary non-polyposis colorectal cancer.

MLH1 wt Allele Synonyms

MLH1 wt Allele, COCA2, FCC2, HNPCC2, MGC5172, MutL Homolog 1, Colon Cancer, nonpolyposis type 2 (E. coli) wt Allele, hMLH1

Terms in MLH1 wt Allele category

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