Cancer Terms

MLL wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> MLL Gene -> MLL wt Allele

MLL wt Allele Definition

Human MLL wild-type allele is located in the vicinity of 11q23 and is approximately 89 kb in length. This allele, which encodes zinc finger protein HRX, is involved in the modulation of transcription by RNA Polymerase II. Several acute leukemias are associated with translocations of the gene.

MLL wt Allele Synonyms

MLL wt Allele, ALL1, HRX, HTRX, MLL, Mixed Lineage Leukemia Gene, Myeloid-Lymphoid Leukemia Gene, Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) wt Allele, TRX1

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