MYC wt Allele

Cancer Terms -> Gene -> Transcription Factor Gene -> MYC Family Gene -> MYC Gene -> MYC wt Allele

MYC wt Allele Definition

Human MYC wild-type allele is located in the vicinity of 8q24.21 and is approximately 5 kb in length. This allele, which encodes myc proto-oncogene protein, plays a role in the regulation of transcription by RNA polymerase II. Burkitt's lymphoma is associated with at least three translocations, t(2;8)(p12;q24), t(8;14)(q24;q32) and t(8;22)(q24;q11) which fuse the gene to the promoter site for either the immunoglobin heavy or light chain genes. In a variety of other tumors the gene is expressed aberrantly.

MYC wt Allele Synonyms

MYC wt Allele, C-MYC, v-MYC Myelocytomatosis Viral Oncogene Homolog (Avian) wt Allele, v-myc Avian Myelocytomatosis Viral Oncogene Cellular Homolog

MYC wt Allele

MYC wt Allele Definition

MYC wt Allele Synonyms

Terms in MYC wt Allele category