Mafosfamide
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Antineoplastic Agent ->
Alkylating Agent ->
Antineoplastic Alkylating Agent ->
Mustard Agent ->
Nitrogen Mustard Compound -> Mafosfamide
Mafosfamide Definition
A synthetic oxazaphosphorine derivative with antineoplastic properties. Mafosfamide alkylates DNA, forming DNA cross-links and inhibiting DNA synthesis. Although closely related to cyclophosphamide, mafosfamide, unlike cyclophosphamide, does not require hepatic activation to generate its active metabolite 4-hydroxy-cyclophosphamide; accordingly, mafosfamide is potentially useful in the intrathecal treatment of neoplastic meningitis. (NCI04)
Mafosfamide Synonyms
Mafosfamide, MAFOSFAMIDE, mafosfamide
Terms in Mafosfamide category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.