Matrix Metalloproteinase-8
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Matrix Metalloproteinase-8 Definition
Expressed in neutrophils by human MMP8 Gene (M10A Peptidase Family), 467-aa 53-kDa (precursor) zinc- and calcium-binding Matrix Metalloproteinase-8 contains a hemopexin-like domain and is stored in secondary granules. Activated by autolytic cleavage, MMP8 degrades fibrillar type I, II, and III interstitial collagens by cleavage in the triple helical domain. (NCI)
Matrix Metalloproteinase-8 Synonyms
Matrix Metalloproteinase-8, CLG1, HNC, MMP8, Neutrophil Collagenase, PMNL Collagenase, PMNL-CL
Terms in Matrix Metalloproteinase-8 category
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