Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

Cancer Terms -> Activity -> Techniques -> Research Techniques -> Physical Chemical Techniques -> Spectrometry -> Mass Spectrometry -> Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Definition

A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample- matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis. (CHI)

Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Synonyms

Matrix-Assisted Laser Desorption Ionization Mass Spectrometry, MALDI, Matrix Assisted Laser Desorption Ionization Mass Spectrometry

Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Definition

Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Synonyms

Terms in Matrix-Assisted Laser Desorption Ionization Mass Spectrometry category