Cancer Terms

Mechlorethamine

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Alkylating Agent -> Antineoplastic Alkylating Agent -> Mustard Agent -> Nitrogen Mustard Compound -> Mechlorethamine

Mechlorethamine Definition

A synthetic agent related to sulphur mustard with antineoplastic and immunosuppressive properties. Nitrogen mustard (a member of a family of chemotherapy agents including cyclophosphamide and chlorambucil) is an irritant and carcinogenic agent metabolized to a highly reactive ethylene immonium derivative; the ethylene immonium derivative alkylates DNA and inhibits DNA replication. This agent also exhibits lympholytic properties. (NCI04)

Mechlorethamine Synonyms

Mechlorethamine, Bis(2-chloroethyl)methylamine, Chlorethazine, Chlormethine, HN 2, MECHLORETHAMINE, Methylbis(beta-chloroethyl)amine, Mustard, Mustine, Nitrogen Mustard, chlorethazine, chloromethine, ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl, mechlorethamine, methylchlorethamine

Terms in Mechlorethamine category



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