Cancer Terms

Metallothionein-3

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Ligand Binding Protein -> Trace Metal Storage Protein -> Metallothionein -> Metallothionein-3

Metallothionein-3 Definition

Metallothionein 3, encoded by the human MT3 gene, belongs to family 1 of the metallothionein superfamily. Metallothionein 3 contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. It binds heavy metals. Metallothionein 3 inhibits survival and neurite formation of cortical neurons in vitro. It is abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the alzheimer's disease (AD) brain. (from Swiss-Prot)

Metallothionein-3 Synonyms

Metallothionein 3, GIF, GIFB, Growth Inhibitory Factor, Growth Inhibitory Factor, Brain, Growth Inhibitory Factor, Neurotrophic, MT-III, MT3, Metallothionein III, Metallothionein-3, Metallothionein-III

Terms in Metallothionein-3 category



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