Cancer Terms

Mitosis and Apoptosis Inhibitor R1530

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> Tyrosine Kinase Inhibitor -> Mitosis and Apoptosis Inhibitor R1530

Mitosis and Apoptosis Inhibitor R1530 Definition

A pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. Mitosis-angiogenesis inhibitor (MAI) R1530 inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta, FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2. In addition, this agents exhibits anti-proliferative activity by initiating mitotic arrest and inducing apoptosis.

Mitosis and Apoptosis Inhibitor R1530 Synonyms

Receptor Tyrosine Kinase Inhibitor R1530, MAI R1530, R1530

Terms in Mitosis and Apoptosis Inhibitor R1530 category



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