Mitosis and Apoptosis Inhibitor R1530
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Mitosis and Apoptosis Inhibitor R1530 Definition
A pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. Mitosis-angiogenesis inhibitor (MAI) R1530 inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta, FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2. In addition, this agents exhibits anti-proliferative activity by initiating mitotic arrest and inducing apoptosis.
Mitosis and Apoptosis Inhibitor R1530 Synonyms
Receptor Tyrosine Kinase Inhibitor R1530, MAI R1530, R1530
Terms in Mitosis and Apoptosis Inhibitor R1530 category
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