Monoclonal Antibody HuG1-M195
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Monoclonal Antibody HuG1-M195 Definition
A humanized recombinant monoclonal antibody directed against CD33, a cell surface antigen found on myeloid leukemia blasts and early hematopoietic progenitor cells. Lintuzumab stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing CD33, resulting in a decrease in tumor burden. The humanized version of this monoclonal antibody exhibits less immunogenicity and improved binding affinity compared to its murine counterpart.
Monoclonal Antibody HuG1-M195 Synonyms
Lintuzumab, Hu-M195 monoclonal antibody, HuG1-M195 monoclonal antibody, MoAb HuG1-M195, MoAb HuM195, Monoclonal Antibody HuG1-M195, Monoclonal Antibody HuM195, monoclonal antibody HuM195 HuG1-M195
Terms in Monoclonal Antibody HuG1-M195 category
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