Cancer Terms

Monoclonal Antibody RG 83852

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Monoclonal Antibody -> Monoclonal Antibody RG 83852

Monoclonal Antibody RG 83852 Definition

A murine monoclonal antibody directed against the human epidermal growth factor receptor (EGFR). Monoclonal antibody RG 83852 binds to the EGFR, inhibiting the high-affinity binding of epidermal growth factor (EGF) and receptor activation. Overexpression of EGFR, a tyrosine kinase, and its upregulated activity have been implicated in the pathogeneses of several malignancies. (NCI04)

Monoclonal Antibody RG 83852 Synonyms

Monoclonal Antibody RG 83852, MOAB RG 83852

Terms in Monoclonal Antibody RG 83852 category



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