Mothers Against Decapentaplegic Homolog-4 Protein
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Mothers Against Decapentaplegic Homolog-4 Protein Definition
The SMAD4 tumor suppressor protein specifically recognizes an eight base pair palindromic DNA sequence and is critical for transmitting TGFB, and related cytokine signals, to the cell nucleus to mediate transcriptional activation of target genes. The MADH4 gene is a cloned gene for Juvenile Polyposis, associated with colon cancer. (from OMIM 600993 and NCI)
Mothers Against Decapentaplegic Homolog-4 Protein Synonyms
Mothers Against Decapentaplegic Homolog 4, DPC4 Protein, MAD4, MADH4, MAX-Interacting Transcriptional Repressor, SMA- and MAD-Related Protein 4, SMAD4 Protein
Terms in Mothers Against Decapentaplegic Homolog-4 Protein category
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