Mucin Peptide MUC-1
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Mucin Peptide MUC-1 Definition
Mucin is expressed by most glandular epithelia. Tandem repeats characterize the core mucin protein, apomucin; variation of the protein derives from variation in the number of expressed repeats. Native forms of mucin are distinct in size and degree of glycosylation; factors other than the primary structure of apomucin may contribute to these characteristics. Many complex O-linked oligosaccharides are presumably added by glycosyltransferases. Expression is increased in the lactating breast and in breast, ovary, lung, and prostate malignancies. It is a serum marker for breast cancer.
Mucin Peptide MUC-1 Synonyms
Mucin Peptide MUC-1, CA-15-3, CA15-3, CA15-3 Antigen, Cancer Antigen 15-3, Carbohydrate Antigen 15-3, Episialin, Muc1 Mucin, Polymorphic Epithelial Mucin
Terms in Mucin Peptide MUC-1 category
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